Tankless CIP & SIP Combo System

In today’s fast-paced pharmaceutical and bioprocessing industries, maintaining impeccable hygiene and sterility is not just a compliance requirement it’s a business-critical function. The traditional approach of using separate cleaning and sterilization systems is rapidly giving way to smarter, more integrated solutions. One such innovation is the tankless CIP & SIP combo system from Pharmatech Process Equipments, designed to streamline operations, reduce resource use, and guarantee hygiene compliance.

By combining Clean-In-Place technology and Steam-In-Place equipment into one advanced system without the need for internal tanks this solution represents the future of pharmaceutical cleaning and sterilization.

Why Tankless? The Power of Integration

The conventional model involves large, fixed systems with dedicated tanks for detergents, rinse water, and steam sterilization. These setups consume space, demand complex piping, and often slow down production due to cleaning-related downtime. The tankless CIP & SIP combo system changes that.

Pharmatech Process Equipments CIP Mobile tankless system connects directly to external utilities, eliminating the need for onboard storage. This not only reduces equipment footprint but allows manufacturers to move a single mobile unit between multiple production lines. It’s a flexible, scalable solution that supports continuous production while maintaining the highest hygiene standards.

Advanced Clean-In-Place Technology

At the heart of the system is a highly intelligent Clean-In-Place technology module. Designed to meet 3A Sanitary Standards and cGMP guidelines, it delivers effective and repeatable cleaning without disassembly. Key features include:

  • Reduced water and chemical consumption
  • Real-time monitoring and control of flow, pressure, and temperature
  • Automated data acquisition and cleaning reports
  • Biofilm mitigation strategies to eliminate microbial buildup

More than just a cleaner, this is an intelligent cleaning system. It continuously analyses data from each cleaning cycle to adjust parameters for subsequent runs. This self-optimization improves consistency and reduces the risk of contamination between batches critical in regulated environments.

Precision Sterilization with SIP

  • Once cleaning is complete, the unit transitions into sterilization mode, functioning as a highly effective automated sterilization systemPharmatech Process Equipments SIP process utilizes high-quality steam introduced strategically to eliminate all viable microorganisms within vessels, transfer lines, or process equipment.

    The SIP sequence follows industry-leading standards:

    • Initial cleaning using CIP
    • Introduction of steam at high points to purge air
    • Real-time temperature monitoring using low-point trap valves
    • Temperature hold times to ensure full sterilization
    • Post-process cooling for safety and readiness

    This dual-function capability makes the Pharmatech Process Equipments tankless CIP/SIP combo system ideal for facilities handling multiple sterile production lines. The seamless transition between cleaning and sterilization reduces downtime and simplifies compliance documentation.

Built for Compliance and Sustainability

Meeting global hygiene and safety regulations is embedded in every aspect of Pharmatech Process Equipments design. This cGMP compliant sterilization system supports ISO 9001:2015 standards and holds a CE and ‘U’ Stamp certification, making it suitable for deployment in USFDA-regulated and EU-GMP manufacturing sites.

Features that support validation and compliance include:

  • Precise recording of temperature at critical control points
  • Acoustic and pressure-based advanced leak detection
  • Integration with eco-friendly cleaning agents
  • Augmented reality (AR) support for operator guidance and remote maintenance

 

Technical Highlights

Engineered for high-performance and flexibility, the CIP Mobile tankless system is equipped with:

  • PLC & HMI-based automation for seamless programming and control with one touch operation
  • SS316L stainless steel construction with <0.6 Ra µm internal finish
  • Skid-mounted design with utility panel for plug-and-play integration
  • Steam pressure regulator with filter housing assembly to ensure steam purity
  • Temperature sensors and flow meters for real-time process feedback
  • Sanitary valves and piping designed to ASME BPE standards for hygiene and ease of cleaning
  • Air vent filters, pressure safety valves, and condensate traps to ensure safe and effective operation
  • Complete IQ/OQ/DQ documentation and traceable calibration certificates for validation support

These advanced features enable manufacturers to meet stringent regulatory standards while enhancing process efficiency, safety, and reliability.

Scalable Pharmaceutical Cleaning Solutions

Whether you’re manufacturing biologics, vaccines, injectables, or sensitive cosmetic formulations, the tankless CIP & SIP combo system offers clear advantages over legacy setups. Its mobile design makes it perfect for multipurpose plants, while its intelligent software makes validation easier for QA teams.

Use cases include:

  • Bioreactor and fermentor cleaning
  • Holding tank and pipeline sterilization
  • Sterile formulation and filling line sanitation
  • Cleanroom equipment turnaround between batches

Because it’s a pharmaceutical cleaning solution built for mobility, you don’t need to install duplicate systems across each line. The same tankless CIP & SIP Combo Mobile system can move from zone to zone, executing programmable cleaning and sterilization recipes with full audit trail support.

Why Pharmatech Process Equipments?

Pharmatech isn’t just a supplier it’s an innovation partner to pharmaceutical manufacturers. With decades of expertise in pharmaceutical cleaning solutions and process equipment design, Pharmatech delivers intelligent, compliant, and scalable systems that meet the evolving needs of the industry.

Their Pharmatech tankless CIP/SIP system is a culmination of years of research, engineering precision, and field experience. Backed by global support, turnkey project execution, and in-house validation services, Pharmatech ensures your production never skips a beat.

The Future of Cleaning and Sterilization is Here

For companies seeking to improve cleanroom efficiency, reduce downtime, and comply with strict regulatory standards, the tankless CIP & SIP combo system offers a smart, future-ready solution.

Its integration of Clean-In-Place technologySteam-In-Place equipment, and intelligent software transforms what used to be a resource-heavy process into one that’s lean, precise, and sustainable.

Contact Pharmatech Process Equipments today to learn how their tankless system can enhance your sterile process workflows while maximizing operational uptime.

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