Liquid Oral
Pharmatech can offer & develop solution preparation system from Manual – Semi automatic to fully Automatic control.
Oral liquids are homogeneous liquid preparations usually contains a solution an emulsion or a suspension of one or more active ingredient in liquid base. They are prepared for oral administration either as such or after dilution.
They may contain other substances such as suitable dispersing solubilizing, wetting, emulsifying, stabilizing, suspending, thickening agents and antimicrobial substances for preservation, sweetening agents, flavoring agents and permitted coloring agents.
Type of Oral solutions include
- Syrup
- Oral Suspension
- Oral Solution
- Oral Drop
- Oral Emulsion
- Mixture
- Linctus
- Elixir
Complete Automation System
Complete automatic operation with PLC with all related auto valves, operating steps, cycles, controls, recipe management, & CIP cleaning validation supported by 21 CFR PART-11 compliance, suitability of SCADA etc.
Semi-Automatic System
Semi auto system with jacket valve automation for temp control of heating / cooling cycle & CIP operation steps & records.
Manual System
Manual operations with few options of recording like temperature, RPM, time with chart recorder.
Benefits of Automatic Control System
- Modular design and installation minimizes the time for site work & project execution.
- Automatic manufacturing process controls offer consistent, predictable & verifiable operations.
- It avoids manual intervention & mistakes during operations.
- It provides stable and controlled quality of the product.
Key Features
- Automatic process operations
- On line filtration & cleanability
- Inbuilt automatic CIP system
- Automated control system with USFDA, 21 CFR PART 11 & GAMP-5.
Pharmatech offers customize solution with conceptual design, engineering, manufacturing and operations compliances to get whole and complete workability of the system.
There are key features shall be considered based on client’s requirement.
Automatic Utility Module
- Temperature control
- Nitrogen Purging control
- Vent control
Automatic Drainage Module
- Automatic Heating and cooling control
- Air purging prior to cooling to avoid thermal Jerk
- Steam trap By-pass draining when needed
Automatic Processing vessel
- Vacuum, vent and feed controls
- Bottom mounted mechanical agitator
- Balanced load cell weighing system
- Dynamic Spray ball for CIP
Inter-Connecting Piping, Valves and Instruments
- ERW SS 316L Tubes with Ra≤ 0.6 µm internally and Ra≤ 0.8 µm externally
- Electropolish Tubes shall be available with Ra ≤ 0.4µm
- Pneumatic two-way valves with automatic control to shut on and shut off function.
- Various Instruments like Temp. Sensor/ Temp. Transmitter, Conductivity Sensor & Analyzer, pH Sensor & Analyzer, Pressure Gauge etc. shall be integrated.